2017 Symposium

The Second Annual Canine Comparative Oncology Symposium was held on February 17, 2017 from 7:30am to 6:00pm at the JB Duke Hotel in Durham, North Carolina. This day long symposium was an exciting opportunity that brought together leaders in this field and highlight comparative oncology work being done at both Duke University and NC State University.

2017 Symposium Details

Keynote Speaker:

Cheryl London, DVM, PhD, Diplomate ACVIM (Oncology)
Professor, The Thekla R. and Donald B. Shackelford Professorship in Canine Medicine
Ohio State College of Veterinary Medicine

Location:

JB Duke Hotel
230 Science Drive
Durham, North Carolina 27710

2017 Presentations

Welcome, Overview of Pilot Project RFA and Awardee Presentations  
- Paul Lunn, BVSc, MS, PhD, MRCVS, NCSU College of Veterinary Medicine

A Phase I Clinical Trial of CP-DOX in Dogs:  A Novel Nanoparticle Formation of an Old Drug  
-    Ashutosh Chilkoti, PhD, Duke Cancer Institute
-    Steven Suter, PhD, NCSU College of Veterinary Medicine

Development of a Personalized Medicine Pipeline for Treatment of Sarcomas/
A Cross Species Genomic Analysis of Osteosarcoma:  Implications for Novel Therapeutic Approaches  
-    Matthew Breen, PhD, NCSU College of Veterinary Medicine
-    William Eward, MD, DVM, Duke Cancer Institute

Identification of Carcinogen-Induced Mutational Signatures in Human and Canine Bladder Cancer  
-    Brant Inman, MD, Duke Cancer Institute
-    Matthew Breen, PhD, NCSU College of Veterinary Medicine

Immunology Opportunities

Human B Cell Immunotherapies – Bench to Bedside  
-    Thomas Tedder, PhD, Duke Cancer Institute

PD-L1 Expression and Signaling by Tumors and Myeloid Cells: Comparative Studies in Mice and Dogs  
-    Steven Dow, DVM, PhD, Colorado State University

Of Mice & Men (and Dogs!): Development of a Therapeutic Xenogeneic DNA Vaccine for Melanoma and other Spontaneous Cancers  
-    Philip Bergman, DVM, MS, PhD, VCA Clinical Studies

Immunotherapy for Brain Tumors  
-    John Sampson, MD, PhD, MHSc, MBA, Duke Cancer Institute

Panel Discussion
-    Mark Dewhirst, DVM, PhD, Duke Cancer Institute (Moderator)
-    Paul Hess, DVM, PhD, NCSU College of Veterinary Medicine 
-    Kent Weinhold, PhD, Duke Cancer Institute  
-    Beverly Teicher, PhD, National Cancer Institute  
-    Eric Bernhard, PhD, National Cancer Institute
-    Tona Gilmer, PhD, XRad Therapeutics

Keynote Address

Leveraging Comparative Oncology to Maximize Translational Outcomes  
-    Cheryl London, DVM, PhD, The Ohio State University College of Veterinary Medicine

General Discussion

Closing Remarks

-    Rodney Page, DVM, MS, Colorado State University
-    Michael Kastan, MD, PhD, Duke Cancer Institute

Poster Session and Refreshments