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2018 Symposium

The Third Annual Canine Comparative Oncology Symposium was held on February 23, 2018 from 7:30am to 6:00pm at the Durham Convention Center in Durham, North Carolina. This daylong symposium was an exciting opportunity that brought together leaders in this field and highlight comparative oncology work being done at both Duke University and NC State University.

2018 Symposium Details

Keynote Speaker: 

Chi Van Dang, MD, PhD
Scientific Director, Ludwig Institute for Cancer Research
Professor, The Wistar Institute 


Durham Convention Center
301 West Morgan Street
Durham, North Carolina 27701 

Welcome Remarks 
Michael Kastan, MD, PhD, Duke Cancer Institute

2018 Presentations:

Overview of Pilot Project RFA and Awardee Presentations 

*Slides not available*
A Phase II Clinical Trial and Pharmacodynamics Study of CP-DOX in Dogs
Ashutosh Chilkoti, PhD and Steven Suter, DVM, PhD, Diplomate ACVIM 

A Mouse to Dog to Human (MDH) Drug Discovery Pipeline 
William Eward, MD, DVM and Matthew Breen, PhD 

Investigating the Dog as a Preclinical Model for Melanoma Therapy Targeting the Long Non-Coding RNA SAMMSON 
Shiaowen David Hsu, MD, PhD and Jennifer Luff, VMD, PhD 

Comparative Analysis of the Impact of BRAF Mutations in Bladder Cancer – A Marker of Advancing Disease? 
Matthew Breen, PhD and Brant Inman, MD 

Imaging Cycling Hypoxia in Canine Tumors During Radiotherapy Dosing 
Hiroto Yoshikawa, DVM, PhD and Xiaofeng Steve Zhang, PhD 

Pushing Forward in Comparative Oncology: Stories From the Frontier 

Limb Salvage in the Age of Regenerative Medicine: Pitfalls, Potential and Solutions 
Nicole Ehrhart, VMD, Diplomate ACVS, Colorado State University 

Comparative Immuno-Oncology in the Precision Medicine and Cancer Moonshot Era: the NCI Perspective 
Toby Hecht, PhD, National Cancer Institute 

Canine CARs - Driving the Model Tesla 
Nicola Mason, PhD, BVetMed, University of Pennsylvania 

Poster Session & Lunch 

Poster Awardee Presentations 

Matthew Breen, PhD (Moderator)  

Catherine Wise ,
NCSU College of Veterinary Medicine 

Suzanne Bartholf DeWitt, DVM ,
Duke Cancer Institute 

Paige Nemec ,
NCSU College of Veterinary Medicine 

Gireesh Reddy ,
Duke Cancer Institute 

Keynote Address 

Michael Kastan, MD, PhD, Duke Cancer Institute 

Cancer Metabolism: Why don’t Whales get Cancer? 
Chi Van Dang, MD, PhD Ludwig Institute for Cancer Research 

Closing Remarks 
Paul Lunn, BVSc, MS, PhD, MRCVS, Diplomate ACVIM, NCSU College of Veterinary Medicine 

Poster Session and Refreshments